Ms Dayani has been described as both president and chief operating officer of Archewell, and is the latest departure from the Sussexes’ team following their former global press secretary and a chief of staff.
A spokesman said: “Ms Dayani has been an integral part of Archewell and we are grateful for her passion, commitment and leadership.
“Ms Dayani was brought on during their parental leave to move the company and its projects forward. She has continued to shape its vision and future successfully.
“Her transition was mutually planned, with intent for the Duke and Duchess to now take full lead of their company.
“There will be no replacement for this position, and Ms Dayani is fully supportive of the Duke and Duchess in their new leadership roles, and they remain friends.”