The Reds are aiming to close the gap on Antonio Conte’s third-placed side before we travel to Chelsea on Saturday.
Ahead of what is sure to be a cracker of a match, here’s everything you need to know…
HOW CAN YOU FOLLOW THE GAME?
This match will be broadcast live on Amazon Prime Video in the UK, with coverage of the 20:15 BST kick-off starting at 18:30 BST.
You can access Amazon Prime Video through your desktop or smart devices, such as Fire TV sticks, games consoles, smartphones and more.
As always, you can watch exclusive build-up and post-match reaction live on MUTV – now available in the United App.
Our pre-match coverage will start at 19:10 BST on Wednesday and will be followed by live radio commentary during the 90 minutes.
WHEN CAN YOU SEE HIGHLIGHTS?
Two-minute highlights of the game will be available from midnight, with more in-depth versions to follow on Thursday.